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Wild Type Beta-2 Microglobulin and DE Loop Mutants Display a Common Fibrillar Architecture
Beta-2 microglobulin (β2m) is the protein responsible for a pathologic condition known as dialysis related amyloidosis. In recent years an important role has been assigned to the peptide loop linking strands D and E (DE loop) in determining β2m stability and amyloid propensity. Several mutants of th...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372401/ https://ncbi.nlm.nih.gov/pubmed/25803608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122449 |
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