Internalization and Down-Regulation of the ALK Receptor in Neuroblastoma Cell Lines upon Monoclonal Antibodies Treatment

Recently, activating mutations of the full length ALK receptor, with two hot spots at positions F1174 and R1275, have been characterized in sporadic cases of neuroblastoma. Here, we report similar basal patterns of ALK phosphorylation between the neuroblastoma IMR-32 cell line, which expresses only...

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Detaylı Bibliyografya
Asıl Yazarlar: Mazot, Pierre, Cazes, Alex, Dingli, Florent, Degoutin, Joffrey, Irinopoulou, Théano, Boutterin, Marie-Claude, Lombard, Bérangère, Loew, Damarys, Hallberg, Bengt, Palmer, Ruth Helen, Delattre, Olivier, Janoueix-Lerosey, Isabelle, Vigny, Marc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316580/
https://ncbi.nlm.nih.gov/pubmed/22479414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033581
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