ALK (anaplastic lymphoma kinase, CD246)-specific CARs: new immunotherapeutic agents for the treatment of pediatric solid tumors

Por Orentas, Rimas J, Lopomo, Paola, Babbitt, William, Vigny, Marc, Mackall, Crystal L
Publicado em 2013

Targeting high-risk pediatric solid tumors with CAR T cells directed against ALK (anaplastic lymphoma kinase, CD246)

Por Walker, Alec, Lopomo, Paola, Babbitt, William, Vigny, Marc, Mackall, Crystal, Orentas, Rimas
Publicado no J Immunother Cancer (2014)

NUMB regulates the endocytosis and activity of the anaplastic lymphoma kinase in an isoform-specific manner

Por Wei, Ran, Liu, Xuguang, Voss, Courtney, Qin, Wentao, Dagnino, Lina, Li, Lei, Vigny, Marc, Li, Shawn Shun-Cheng
Publicado no J Mol Cell Biol (2019)

The Neuroblastoma ALK(I1250T) Mutation Is a Kinase-Dead RTK In Vitro and In Vivo

Por Schönherr, Christina, Ruuth, Kristina, Eriksson, Therese, Yamazaki, Yasuo, Ottmann, Christian, Combaret, Valerie, Vigny, Marc, Kamaraj, Sattu, Palmer, Ruth H, Hallberg, Bengt
Publicado em 2011

Anaplastic Lymphoma Kinase Is a Dependence Receptor Whose Proapoptotic Functions Are Activated by Caspase Cleavage

Por Mourali, Jaouhar, Bénard, Alan, Lourenço, Filipe Calheiros, Monnet, Céline, Greenland, Catherine, Moog-Lutz, Christel, Racaud-Sultan, Claire, Gonzalez-Dunia, Daniel, Vigny, Marc, Mehlen, Patrick, Delsol, Georges, Allouche, Michèle
Publicado em 2006

Internalization and Down-Regulation of the ALK Receptor in Neuroblastoma Cell Lines upon Monoclonal Antibodies Treatment

Por Mazot, Pierre, Cazes, Alex, Dingli, Florent, Degoutin, Joffrey, Irinopoulou, Théano, Boutterin, Marie-Claude, Lombard, Bérangère, Loew, Damarys, Hallberg, Bengt, Palmer, Ruth Helen, Delattre, Olivier, Janoueix-Lerosey, Isabelle, Vigny, Marc
Publicado em 2012

Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase

Por Walker, Alec J., Majzner, Robbie G., Zhang, Ling, Wanhainen, Kelsey, Long, Adrienne H., Nguyen, Sang M., Lopomo, Paola, Vigny, Marc, Fry, Terry J., Orentas, Rimas J., Mackall, Crystal L.
Publicado no Mol Ther (2017)

Nodes of Ranvier and Paranodes in Chronic Acquired Neuropathies

Por Cifuentes-Diaz, Carmen, Dubourg, Odile, Irinopoulou, Theano, Vigny, Marc, Lachkar, Sylvie, Decker, Laurence, Charnay, Patrick, Denisenko, Natalia, Maisonobe, Thierry, Léger, Jean-Marc, Viala, Karine, Hauw, Jean-Jacques, Girault, Jean-Antoine
Publicado em 2011