5′-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity

RIG-I is a cytosolic receptor for non-self RNA that mediates immune responses against viral infections through IFNα/β production. In an attempt to identify novel tools that modulate IFNα/β production, we used SELEX technology to screen RNA aptamers that specifically target RIG-I protein. Most of the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hwang, Sun-Young, Sun, Hwa-Young, Lee, Kwang-Hoon, Oh, Byung-Ha, Cha, Yu Jin, Kim, Byeang Hyean, Yoo, Joo-Yeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315321/
https://ncbi.nlm.nih.gov/pubmed/22127865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1098
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge