The Stress Oncoprotein LEDGF/p75 Interacts with the Methyl CpG Binding Protein MeCP2 and Influences its Transcriptional Activity

The lens epithelium derived growth factor p75 (LEDGF/p75) is a transcription co-activator that promotes resistance to oxidative stress- and chemotherapy-induced cell death. LEDGF/p75 is also known as the dense fine speckles autoantigen of 70 kD (DFS70), and has been implicated in cancer, HIV-AIDS, a...

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Autores principales: Leoh, Lai Sum, Heertum, Bart van, De Rijck, Jan, Filippova, Maria, Rios-Colon, Leslimar, Basu, Anamika, Martinez, Shannalee R., Tungteakkhun, Sandy S., Filippov, Valeri, Christ, Frauke, De Leon, Marino, Debyser, Zeger, Casiano, Carlos A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312617/
https://ncbi.nlm.nih.gov/pubmed/22275515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0314
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