Targeting the stress oncoprotein LEDGF/p75 to sensitize chemoresistant prostate cancer cells to taxanes

Prostate cancer (PCa) is associated with chronic prostate inflammation resulting in activation of stress and pro-survival pathways that contribute to disease progression and chemoresistance. The stress oncoprotein lens epithelium-derived growth factor p75 (LEDGF/p75), also known as DFS70 autoantigen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ríos-Colón, Leslimar, Cajigas-Du Ross, Christina K., Basu, Anamika, Elix, Catherine, Alicea-Polanco, Ivana, Sanchez, Tino W., Radhakrishnan, Vinodh, Chen, Chien-Shing, Casiano, Carlos A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421899/
https://ncbi.nlm.nih.gov/pubmed/28212536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15323
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