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Alternative Splicing and Caspase-Mediated Cleavage Generate Antagonistic Variants of the Stress Oncoprotein LEDGF/p75

There is increasing evidence that an augmented state of cellular oxidative stress modulates the expression of stress genes implicated in diseases associated with health disparities such as certain cancers and diabetes. Lens epithelium–derived growth factor p75 (LEDGF/p75), also known as DFS70 autoan...

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Detalhes bibliográficos
Main Authors: Brown-Bryan, Terry A., Leoh, Lai S., Ganapathy, Vidya, Pacheco, Fabio J., Mediavilla-Varela, Melanie, Filippova, Maria, Linkhart, Thomas A., Gijsbers, Rik, Debyser, Zeger, Casiano, Carlos A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790462/
https://ncbi.nlm.nih.gov/pubmed/18708362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0125
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