Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75

BACKGROUND: Hormone-refractory prostate cancer (HRPC) is characterized by poor response to chemotherapy and high mortality, particularly among African American men when compared to other racial/ethnic groups. It is generally accepted that docetaxel, the standard of care for chemotherapy of HRPC, pri...

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Detalhes bibliográficos
Main Authors: Mediavilla-Varela, Melanie, Pacheco, Fabio J, Almaguel, Frankis, Perez, Jossymar, Sahakian, Eva, Daniels, Tracy R, Leoh, Lai Sum, Padilla, Amelia, Wall, Nathan R, Lilly, Michael B, De Leon, Marino, Casiano, Carlos A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741463/
https://ncbi.nlm.nih.gov/pubmed/19715609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-68
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