Indoleamine 2,3-Dioxygenase: Is It an Immune Suppressor?

Por Soliman, Hatem, Mediavilla-Varela, Melanie, Antonia, Scott
Publicado em 2010

A GM-CSF and CD40L bystander vaccine is effective in a murine breast cancer model

Por Soliman, Hatem, Mediavilla-Varela, Melanie, Antonia, Scott J
Publicado no Breast Cancer (Dove Med Press) (2015)

Tumor-associated Antigen Arrays for the Serological Diagnosis of Cancer

Por Casiano, Carlos A., Mediavilla-Varela, Melanie, Tan, Eng M.
Publicado em 2006

The anti-fibrotic agent pirfenidone synergizes with cisplatin in killing tumor cells and cancer-associated fibroblasts

Por Mediavilla-Varela, Melanie, Boateng, Kingsley, Noyes, David, Antonia, Scott J.
Publicado no BMC Cancer (2016)

Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth

Por Mediavilla-Varela, Melanie, Luddy, Kimberly, Noyes, David, Khalil, Farah K, Neuger, Anthony M, Soliman, Hatem, Antonia, Scott J
Publicado em 2013

Transforming Growth Factor β Signaling Overcomes Dasatinib Resistance in Lung Cancer

Por Gordian, Edna, Li, Jiannong, Pevzner, Yuri, Mediavilla-Varela, Melanie, Luddy, Kimberly, Ohaegbulam, Kim, Daniel, Kenyon G., Haura, Eric B., Muñoz-Antonia, Teresita
Publicado no PLoS One (2014)

Alternative Splicing and Caspase-Mediated Cleavage Generate Antagonistic Variants of the Stress Oncoprotein LEDGF/p75

Por Brown-Bryan, Terry A., Leoh, Lai S., Ganapathy, Vidya, Pacheco, Fabio J., Mediavilla-Varela, Melanie, Filippova, Maria, Linkhart, Thomas A., Gijsbers, Rik, Debyser, Zeger, Casiano, Carlos A.
Publicado em 2008

Docosahexanoic acid antagonizes TNF-α-induced necroptosis by attenuating oxidative stress, ceramide production, lysosomal dysfunction, and autophagic features

Por Pacheco, Fabio J., Almaguel, Frankis G., Evans, Whitney, Rios-Colon, Leslimar, Filippov, Valery, Leoh, Lai S., Rook-Arena, Elizabeth, Mediavilla-Varela, Melanie, De Leon, Marino, Casiano, Carlos A.
Publicado em 2014

Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75

Por Mediavilla-Varela, Melanie, Pacheco, Fabio J, Almaguel, Frankis, Perez, Jossymar, Sahakian, Eva, Daniels, Tracy R, Leoh, Lai Sum, Padilla, Amelia, Wall, Nathan R, Lilly, Michael B, De Leon, Marino, Casiano, Carlos A
Publicado em 2009

LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer

Por Basu, Anamika, Cajigas-Du Ross, Christina K., Rios-Colon, Leslimar, Mediavilla-Varela, Melanie, Daniels-Wells, Tracy R., Leoh, Lai Sum, Rojas, Heather, Banerjee, Hiya, Martinez, Shannalee R., Acevedo-Martinez, Stephanny, Casiano, Carlos A.
Publicado no PLoS One (2016)

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumor cell PD-L1 expression and intratumoral immunosuppression

Por Chen, Limo, Gibbons, Don L., Goswami, Sangeeta, Cortez, Maria Angelica, Ahn, Young-Ho, Byers, Lauren A., Zhang, Xuejun, Yi, Xiaohui, Dwyer, David, Lin, Wei, Diao, Lixia, Wang, Jing, Roybal, Jonathon, Patel, Mayuri, Ungewiss, Christin, Peng, David, Antonia, Scott, Mediavilla-Varela, Melanie, Robertson, Gordon, Suraokar, Milind, Welsh, James W., Erez, Baruch, Wistuba, Ignacio I., Chen, Lieping, Peng, Di, Wang, Shanshan, Ullrich, Stephen E., Heymach, John V., Kurie, Jonathan M., Qin, F. Xiao-Feng
Publicado em 2014