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Pathway Specific Gene Expression Profiling Reveals Oxidative Stress Genes Potentially Regulated by Transcription Co-Activator LEDGF/p75 in Prostate Cancer Cells

BACKGROUND: Lens epithelium-derived growth factor p75 (LEDGF/p75) is a stress survival transcription co-activator and autoantigen that is overexpressed in tumors, including prostate cancer (PCa). This oncoprotein promotes resistance to cell death induced by oxidative stress and chemotherapy by mecha...

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Autors principals: Basu, Anamika, Drame, Awa, Muñoz, Ruben, Gijsbers, Rik, Debyser, Zeger, De Leon, Marino, Casiano, Carlos A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227744/
https://ncbi.nlm.nih.gov/pubmed/21796653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21463
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