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Mechanism of substrate selection by a highly specific CRISPR endoribonuclease
Bacteria and archaea possess adaptive immune systems that rely on small RNAs for defense against invasive genetic elements. CRISPR (clustered regularly interspaced short palindromic repeats) genomic loci are transcribed as long precursor RNAs, which must be enzymatically cleaved to generate mature C...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312554/ https://ncbi.nlm.nih.gov/pubmed/22345129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030882.111 |
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