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GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry
Maintaining hematopoietic stem cell (HSC) quiescence is a critical property for the life-long generation of blood cells. Approximately 75% of cells in a highly enriched long-term repopulating HSC (LT-HSC) pool (Lin(−)Sca1(+)c-Kit(hi)CD150(+)CD48(−)) are quiescent, with only a small percentage of the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311255/ https://ncbi.nlm.nih.gov/pubmed/22267605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-366070 |
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