Cargando...

A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance

Protein abundance must be precisely regulated throughout life, and nowhere is the stringency of this requirement more evident than during T-cell development: A twofold increase in the abundance of transcription factor GATA3 results in thymic lymphoma, while reduced GATA3 leads to diminished T-cell p...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Ku, Chia-Jui, Lim, Kim-Chew, Kalantry, Sundeep, Maillard, Ivan, Engel, James Douglas, Hosoya, Tomonori
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579350/
https://ncbi.nlm.nih.gov/pubmed/26385963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.265025.115
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!