GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion

Allelic exclusion describes the essential immunological process by which feedback repression of sequential DNA rearrangements ensures that only one autosome expresses a functional T or B cell receptor. In wild-type mammals, approximately 60% of cells have recombined the DNA of one T cell receptor β...

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Foilsithe in:Mol Cell Biol
Main Authors: Ku, Chia-Jui, Sekiguchi, JoAnn M., Panwar, Bharat, Guan, Yuanfang, Takahashi, Satoru, Yoh, Keigyou, Maillard, Ivan, Hosoya, Tomonori, Engel, James Douglas
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452726/
https://ncbi.nlm.nih.gov/pubmed/28320875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00052-17
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