GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion

Allelic exclusion describes the essential immunological process by which feedback repression of sequential DNA rearrangements ensures that only one autosome expresses a functional T or B cell receptor. In wild-type mammals, approximately 60% of cells have recombined the DNA of one T cell receptor β...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ku, Chia-Jui, Sekiguchi, JoAnn M., Panwar, Bharat, Guan, Yuanfang, Takahashi, Satoru, Yoh, Keigyou, Maillard, Ivan, Hosoya, Tomonori, Engel, James Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452726/
https://ncbi.nlm.nih.gov/pubmed/28320875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00052-17
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