FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

Little is known about whether autophagic mechanisms are active in hematopoietic stem cells (HSCs) or how they are regulated. FIP200 (200-kDa FAK-family interacting protein) plays important roles in mammalian autophagy and other cellular functions, but its role in hematopoietic cells has not been exa...

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Bibliografiske detaljer
Main Authors: Liu, Fei, Lee, Jae Y., Wei, Huijun, Tanabe, Osamu, Engel, James D., Morrison, Sean J., Guan, Jun-Lin
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321744/
https://ncbi.nlm.nih.gov/pubmed/20716775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-288589
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