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High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase.

We demonstrate that despite lacking a 3'----5' proofreading exonuclease, the Thermus aquaticus (Taq) DNA polymerase can catalyze highly accurate DNA synthesis in vitro. Under defined reaction conditions, the error rate per nucleotide polymerized at 70 degrees C can be as low as 10(-5) for...

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Bibliografiset tiedot
Päätekijät: Eckert, K A, Kunkel, T A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1990
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC331072/
https://ncbi.nlm.nih.gov/pubmed/2374708
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