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Thermodynamics of the binding of Thermus aquaticus DNA polymerase to primed-template DNA

DNA binding of the Type 1 DNA polymerase from Thermus aquaticus (Taq polymerase) and its Klentaq large fragment domain have been studied as a function of temperature. Equilibrium binding assays were performed from 5 to 70°C using a fluorescence anisotropy assay and from 10 to 60°C using isothermal t...

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Main Authors: Datta, Kausiki, LiCata, Vince J.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC206472/
https://ncbi.nlm.nih.gov/pubmed/14500822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg774
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