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BiHelix: Towards de novo Structure Prediction of an Ensemble of G-Protein Coupled Receptor Conformations
G-Protein Coupled Receptors (GPCRs) play a critical role in cellular signal transduction pathways and are prominent therapeutic targets. Recently there has been major progress in obtaining experimental structures for a few GPCRs. Each GPCR, however, exhibits multiple conformations that play a role i...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310341/ https://ncbi.nlm.nih.gov/pubmed/22173949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23216 |
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