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Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor

The glucagon-like peptide 1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) involved in insulin synthesis and regulation; therefore, it is an important drug target for treatment of diabetes. However, GLP1R is a member of the class B1 family of GPCRs for which there are no experimental struct...

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Bibliografiske detaljer
Main Authors: Kirkpatrick, Andrea, Heo, Jiyoung, Abrol, Ravinder, Goddard, William A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523846/
https://ncbi.nlm.nih.gov/pubmed/23169631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218051109
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