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Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptor
The glucagon-like peptide 1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) involved in insulin synthesis and regulation; therefore, it is an important drug target for treatment of diabetes. However, GLP1R is a member of the class B1 family of GPCRs for which there are no experimental struct...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3523846/ https://ncbi.nlm.nih.gov/pubmed/23169631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218051109 |
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