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Hydrocarbon-stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor
Glucagon-like peptide 1 (GLP-1) is a natural peptide agonist of the GLP-1 receptor (GLP-1R) found on pancreatic β-cells. Engagement of the receptor stimulates insulin release in a glucose-dependent fashion and increases β-cell mass, two ideal features for pharmacologic management of type 2 diabetes....
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| Udgivet i: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7366314/ https://ncbi.nlm.nih.gov/pubmed/32348108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00308 |
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