Biophysical Determinants for Cellular Uptake of Hydrocarbon-Stapled Peptide Helices

Hydrocarbon-stapled peptides are a class of bioactive alpha-helical ligands developed to dissect and target protein interactions. While there is consensus that stapled peptides can be effective chemical tools for investigating protein regulation, their broader utility for therapeutic modulation of i...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem Biol
Asıl Yazarlar: Bird, Gregory H., Mazzola, Emanuele, Opoku-Nsiah, Kwadwo, Lammert, Margaret A., Godes, Marina, Neuberg, Donna S., Walensky, Loren D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055751/
https://ncbi.nlm.nih.gov/pubmed/27547919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2153
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