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Biophysical Determinants for Cellular Uptake of Hydrocarbon-Stapled Peptide Helices

Hydrocarbon-stapled peptides are a class of bioactive alpha-helical ligands developed to dissect and target protein interactions. While there is consensus that stapled peptides can be effective chemical tools for investigating protein regulation, their broader utility for therapeutic modulation of i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Chem Biol
Päätekijät: Bird, Gregory H., Mazzola, Emanuele, Opoku-Nsiah, Kwadwo, Lammert, Margaret A., Godes, Marina, Neuberg, Donna S., Walensky, Loren D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055751/
https://ncbi.nlm.nih.gov/pubmed/27547919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2153
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