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Characterizing and Predicting the Functional and Conformational Diversity of Seven-Transmembrane Proteins

The activation of seven-transmembrane receptors (7TMRs) allows cells to sense their environment and convert extracellular signals (like hormone binding) into intracellular signals (through G protein-coupled and/or β arrestin-coupled pathways). A single 7TMR is capable of transducing a wide spectrum...

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Detalhes bibliográficos
Main Authors: Abrol, Ravinder, Kim, Soo-Kyung, Bray, Jenelle K., Griffith, Adam R., Goddard, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286597/
https://ncbi.nlm.nih.gov/pubmed/22197575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2011.12.005
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