Cargando...

SuperBiHelix method for predicting the pleiotropic ensemble of G-protein–coupled receptor conformations

There is overwhelming evidence that G-protein–coupled receptors (GPCRs) exhibit several distinct low-energy conformations, each of which might favor binding to different ligands and/or lead to different downstream functions. Understanding the function of such proteins requires knowledge of the ensem...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Bray, Jenelle K., Abrol, Ravinder, Goddard, William A., Trzaskowski, Bartosz, Scott, Caitlin E.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890820/
https://ncbi.nlm.nih.gov/pubmed/24344284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321233111
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!