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BiHelix: Towards de novo Structure Prediction of an Ensemble of G-Protein Coupled Receptor Conformations

G-Protein Coupled Receptors (GPCRs) play a critical role in cellular signal transduction pathways and are prominent therapeutic targets. Recently there has been major progress in obtaining experimental structures for a few GPCRs. Each GPCR, however, exhibits multiple conformations that play a role i...

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Sonraí Bibleagrafaíochta
Main Authors: Abrol, Ravinder, Bray, Jenelle K., Goddard, William A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310341/
https://ncbi.nlm.nih.gov/pubmed/22173949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23216
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