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Structure-based prediction of subtype-selectivity of Histamine H(3) receptor selective antagonists in clinical trials

Histamine receptors (HRs) are excellent drug targets for the treatment of diseases such as schizophrenia, psychosis, depression, migraine, allergies, asthma ulcers, and hypertension. Among them, the human H(3) Histamine receptor (hH(3)HR) antagonists have been proposed for specific therapeutic appli...

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Autors principals: Kim, Soo-Kyung, Fristrup, Peter, Abrol, Ravinder, Goddard, William A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246544/
https://ncbi.nlm.nih.gov/pubmed/22035233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci200435b
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