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Structure-based prediction of subtype-selectivity of Histamine H(3) receptor selective antagonists in clinical trials

Histamine receptors (HRs) are excellent drug targets for the treatment of diseases such as schizophrenia, psychosis, depression, migraine, allergies, asthma ulcers, and hypertension. Among them, the human H(3) Histamine receptor (hH(3)HR) antagonists have been proposed for specific therapeutic appli...

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Detalhes bibliográficos
Main Authors: Kim, Soo-Kyung, Fristrup, Peter, Abrol, Ravinder, Goddard, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246544/
https://ncbi.nlm.nih.gov/pubmed/22035233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci200435b
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