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Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications

The understanding of G-protein coupled receptors (GPCRs) is undergoing a revolution due to increased information about their signaling and the experimental determination of structures for more than 25 receptors. The availability of at least one receptor structure for each of the GPCR classes, well s...

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Publicat a:PLoS Comput Biol
Autors principals: Cvicek, Vaclav, Goddard, William A., Abrol, Ravinder
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814114/
https://ncbi.nlm.nih.gov/pubmed/27028541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004805
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