Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms

The recent proliferation of published TRP channel structures provides a foundation for understanding the diverse functional properties of this important family of ion channel proteins. To facilitate mechanistic investigations, we constructed a structure-based alignment of the transmembrane domains o...

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Veröffentlicht in:eLife
Hauptverfasser: Huffer, Katherine E, Aleksandrova, Antoniya A, Jara-Oseguera, Andrés, Forrest, Lucy R, Swartz, Kenton J
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Structural Biology and Molecular Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7431192/
https://ncbi.nlm.nih.gov/pubmed/32804077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58660
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