Cytosolic Bax: DOES IT REQUIRE BINDING PROTEINS TO KEEP ITS PRO-APOPTOTIC ACTIVITY IN CHECK?

Bax is kept inactive in the cytosol by refolding its C-terminal transmembrane domain into the hydrophobic binding pocket. Although energetic calculations predicted this conformation to be stable, numerous Bax binding proteins were reported and suggested to further stabilize inactive Bax. Unfortunate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vogel, Sandra, Raulf, Nina, Bregenhorn, Stephanie, Biniossek, Martin L., Maurer, Ulrich, Czabotar, Peter, Borner, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308772/
https://ncbi.nlm.nih.gov/pubmed/22277657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248906
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados