Cargando...
Allosteric Sensitization of Pro-Apoptotic BAX
BAX is a critical apoptotic regulator that can be transformed from a cytosolic monomer into a lethal mitochondrial oligomer, yet drug strategies to modulate it are underdeveloped due to longstanding difficulties in conducting screens on this aggregation-prone protein. Here, we overcame prior challen...
Gardado en:
| Publicado en: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5675120/ https://ncbi.nlm.nih.gov/pubmed/28692068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2433 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|