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Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

BCL-2 family proteins converge at the mitochondrial outer membrane to regulate apoptosis and maintain the critical balance between cellular life and death. This physiologic process is essential to organism homeostasis and relies on protein-protein and protein-lipid interactions among BCL-2 family pr...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Cohen, Daniel T., Wales, Thomas E., McHenry, Matthew W., Engen, John R., Walensky, Loren D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343539/
https://ncbi.nlm.nih.gov/pubmed/32160532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.057
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