A carregar...
Direct and selective small-molecule activation of proapoptotic BAX
BCL-2 family proteins are key regulators of the apoptotic pathway. Antiapoptotic members sequester the BCL-2 homology 3 (BH3) death domains of proapoptotic members such as BAX to maintain cell survival. The antiapoptotic BH3-binding groove has been successfully targeted to reactivate apoptosis in ca...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617124/ https://ncbi.nlm.nih.gov/pubmed/22634637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.995 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|