Laddar...

Conformational control of Bax localization and apoptotic activity by Pro168

In healthy cells, Bax resides inactive in the cytosol because its COOH-terminal transmembrane region (TMB) is tucked into a hydrophobic pocket. During apoptosis, Bax undergoes a conformational change involving NH(2)-terminal exposure and translocates to mitochondria to release apoptogenic factors. H...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Schinzel, Anna, Kaufmann, Thomas, Schuler, Martin, Martinalbo, Jorge, Grubb, David, Borner, Christoph
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172067/
https://ncbi.nlm.nih.gov/pubmed/15037603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200309013
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!