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Conformational Rearrangements in the Pro-apoptotic Protein, Bax, as It Inserts into Mitochondria: A CELLULAR DEATH SWITCH

The B-cell lymphoma 2 (Bcl-2) family of proteins regulates the activation of apoptosis through the mitochondria pathway. Pro- and anti-apoptotic members of this family keep each other in check until the correct time to commit to apoptosis. The point of no return for this commitment is the permeabili...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gahl, Robert F., He, Yi, Yu, Shiqin, Tjandra, Nico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239635/
https://ncbi.nlm.nih.gov/pubmed/25315775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.593897
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