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Bcl-2 proteins bid and bax form a network to permeabilize the mitochondria at the onset of apoptosis
The most critical step in the initiation of apoptosis is the activation of the Bcl-2 family of proteins to oligomerize and permeabilize the outer-mitochondrial membrane (OMM). As this step results in the irreversible release of factors that enhance cellular degradation, it is the point of no return...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5133987/ https://ncbi.nlm.nih.gov/pubmed/27763642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.320 |
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