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Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis
Bax promotes cell death by permeabilizing mitochondrial outer membranes by an unresolved mechanism. However, in cells lacking the gene c-myc, membrane permeabilization by Bax is blocked by changes in the mitochondria that prevent Bax oligomerization. Drug-treated c-myc null cells and cells expressin...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150878/ https://ncbi.nlm.nih.gov/pubmed/15920484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600675 |
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