Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria

The ability of the c-Myc oncoprotein to potentiate apoptosis has been well documented; however, the mechanism of action remains ill defined. We have previously identified spatially distinct apoptotic pathways within the same cell that are differentially inhibited by Bcl-2 targeted to either the mito...

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Detaylı Bibliyografya
Asıl Yazarlar: Soucie, Erinn L., Annis, Matthew G., Sedivy, John, Filmus, Jorge, Leber, Brian, Andrews, David W., Penn, Linda Z.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Cell Growth and Development
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC87151/
https://ncbi.nlm.nih.gov/pubmed/11416148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4725-4736.2001
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