Mutagenesis of the BH3 Domain of BAX Identifies Residues Critical for Dimerization and Killing

The BCL-2 family of proteins is comprised of proapoptotic as well as antiapoptotic members (S. N. Farrow and R. Brown, Curr. Opin. Genet. Dev. 6:45–49, 1996). A prominent death agonist, BAX, forms homodimers and heterodimerizes with multiple antiapoptotic members. Death agonists have an amphipathic...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Wang, Kun, Gross, Atan, Waksman, Gabriel, Korsmeyer, Stanley J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.10.6083
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