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Channel formation by antiapoptotic protein Bcl-2

Bcl-2 is the prototypical member of a large family of apoptosis-regulating proteins, consisting of blockers and promoters of cell death. The three-dimensional structure of a Bcl-2 homologue, Bcl-X(L), suggests striking similarity to the pore-forming domains of diphtheria toxin and the bacterial coli...

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Autori principali: Schendel, Sharon L., Xie, Zhihua, Montal, Myrta Oblatt, Matsuyama, Shigemi, Montal, Mauricio, Reed, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC24640/
https://ncbi.nlm.nih.gov/pubmed/9144199
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