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Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria

The ability of the c-Myc oncoprotein to potentiate apoptosis has been well documented; however, the mechanism of action remains ill defined. We have previously identified spatially distinct apoptotic pathways within the same cell that are differentially inhibited by Bcl-2 targeted to either the mito...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Soucie, Erinn L., Annis, Matthew G., Sedivy, John, Filmus, Jorge, Leber, Brian, Andrews, David W., Penn, Linda Z.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416148/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.14.4725-4736.2001
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