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c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

Expression of c-Myc sensitizes cells to a wide range of pro-apoptotic stimuli. We here show that this pro-apoptotic effect is mediated through release of mitochondrial holocytochrome c into the cytosol. First, activation of c-Myc triggers release of cytochrome c from mitochondria. This release is ca...

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Detaylı Bibliyografya
Asıl Yazarlar: Juin, Philippe, Hueber, Anne-Odile, Littlewood, Trevor, Evan, Gerard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC316765/
https://ncbi.nlm.nih.gov/pubmed/10364155
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