c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
Expression of c-Myc sensitizes cells to a wide range of pro-apoptotic stimuli. We here show that this pro-apoptotic effect is mediated through release of mitochondrial holocytochrome c into the cytosol. First, activation of c-Myc triggers release of cytochrome c from mitochondria. This release is ca...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
1999
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.11.1367 |
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