c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
Expression of c-Myc sensitizes cells to a wide range of pro-apoptotic stimuli. We here show that this pro-apoptotic effect is mediated through release of mitochondrial holocytochrome c into the cytosol. First, activation of c-Myc triggers release of cytochrome c from mitochondria. This release is ca...
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| 發表在: | Genes Dev |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
1999
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.11.1367 |
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