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Dopaminergic Signaling and Striatal Neurodegeneration in Huntington's Disease
Huntington's disease (HD) is a neurodegenerative disorder caused by polyglutamine (polyQ) expansion in Huntingtin protein (Htt). PolyQ expansion in Htt(exp) causes selective degeneration of striatal medium spiny neurons (MSNs) in HD patients. Striatal MSN neurons receive glutamatergic input fro...
Tallennettuna:
| Päätekijät: | , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Society for Neuroscience
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307545/ https://ncbi.nlm.nih.gov/pubmed/17652581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1396-07.2007 |
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