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Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 3
Spinocerebellar ataxia type 3 (SCA3), also known as Machado–Joseph disease (MJD), is an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion in ataxin-3 (ATX3; MJD1) protein. In biochemical experiments, we demonstrate that mutant ATX3(exp) specifically associated with th...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663415/ https://ncbi.nlm.nih.gov/pubmed/19036964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3909-08.2008 |
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