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Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 2
Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited, neurodegenerative disease caused by an expansion of polyglutamine tracts in the cytosolic protein ataxin-2 (Atx2). Cerebellar Purkinje cells (PCs) are predominantly affected in SCA2. The cause of PC degeneration in SCA2 is un...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749883/ https://ncbi.nlm.nih.gov/pubmed/19625506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0660-09.2009 |
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