Cyclin D1 Gene Ablation Confers Neuroprotection in Traumatic Brain Injury

Cell cycle activation (CCA) is one of the principal secondary injury mechanisms following brain trauma, and it leads to neuronal cell death, microglial activation, and neurological dysfunction. Cyclin D1 (CD1) is a key modulator of CCA and is upregulated in neurons and microglia following traumatic...

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Autors principals: Kabadi, Shruti V., Stoica, Bogdan A., Loane, David J., Byrnes, Kimberly R., Hanscom, Marie, Cabatbat, Rainier M., Tan, Ming T., Faden, Alan I.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303105/
https://ncbi.nlm.nih.gov/pubmed/21895533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2011.1980
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