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CR8, a Selective and Potent CDK Inhibitor, Provides Neuroprotection in Experimental Traumatic Brain Injury

Traumatic brain injury (TBI) induces secondary injury mechanisms, including cell cycle activation (CCA), that leads to neuronal death and neurological dysfunction. We recently reported that delayed administration of roscovitine, a relatively selective cyclin-dependent kinase (CDK) inhibitor, inhibit...

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書誌詳細
主要な著者: Kabadi, Shruti V., Stoica, Bogdan A., Hanscom, Marie, Loane, David J., Kharebava, Giorgi, Murray II, Michael G., Cabatbat, Rainier M., Faden, Alan I.
フォーマット: Artigo
言語:Inglês
出版事項: Springer-Verlag 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324621/
https://ncbi.nlm.nih.gov/pubmed/22167461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-011-0095-4
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