Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury

Neuronal programmed cell death (PCD) contributes to delayed tissue damage after traumatic brain injury (TBI). Both caspase-dependent and caspase-independent mechanisms have been implicated, with the latter including apoptosis inducing factor (AIF). The peptidyl-proplyl isomerase Cyclophilin A (CypA)...

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Sonraí Bibleagrafaíochta
Main Authors: Piao, Chun-Shu, Loane, David J., Stoica, Bogdan A., Li, Shihong, Hanscom, Marie, Cabatbat, Rainier, Blomgren, Klas, Faden, Alan I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352990/
https://ncbi.nlm.nih.gov/pubmed/22426396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.03.018
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